We are too! We'll be going toward the end of October, MEA weekend for you Minnesotans. It will be me, the wife and another couple. This will be the first time the four of us have travelled together, so it should be a very interesting experience. We have all been discussing what we would like to do while we are out there. I've composed a list of typically tourist-y things (visit Alcatraz, ride a streetcar, etc.), but the one I'm most excited about is renting a bike and riding it across the Golden Gate bridge.
The idea hadn't even occurred to me on my own. I was googling San Fran, looking for interesting things to do and found several bike rental outfits. For about $50 (give or take) you can get outfitted with a bike and a map and turned loose in the city. The basic route is to get out of Fisherman's Wharf and cross the Golden Gate into Sausalito. Once there you can either continue into Tiburon or just stay put in Sausalito. Either way, a ferry ride back across the bay is included. It sounds just awesome.
If anybody has any experience with San Fran biking, let me know! I'd also be interested in any cool San Fran things that I'm not likely to find on the Official San Fran website.